BDBM50192242 CHEMBL3922535::US10239870, Example 177

SMILES Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)nnc1-c1ccc(nc1)C#N

InChI Key InChIKey=LMYXDMLXVWZVJJ-QPPBQGQZSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192242   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Indivior

US Patent
LigandPNGBDBM50192242(CHEMBL3922535 | US10239870, Example 177)
Affinity DataKi:  1.45nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM50192242(CHEMBL3922535 | US10239870, Example 177)
Affinity DataKi:  794nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...More data for this Ligand-Target Pair
In DepthDetails US Patent