BDBM50193833 CHEMBL220018::N-[(S)-1-((3S,8aS)-3-benzyl-hexahydro-pyrrolo[1,2-a]pyrazine-2-carbonyl)-4-guanidino-butyl]-3-(1H-indol-3-yl)-propionamide

SMILES NC(N)=NCCC[C@H](NC(=O)CCc1c[nH]c2ccccc12)C(=O)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1

InChI Key InChIKey=QJJUWWQDEUFNRO-VBOOUTDYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50193833   

TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC5R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC4R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC3R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50193833(CHEMBL220018 | N-[(S)-1-((3S,8aS)-3-benzyl-hexahyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human MC1R expressed in HEK293 cells assessed by measuring intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed