BDBM50193918 3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-enyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide::CHEMBL385955

SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(=O)NS(=O)(=O)c2cccs2)ccc1OCc1ccccc1

InChI Key InChIKey=JJCRBJIDRBAGOY-AEVILUGTSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50193918   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  840nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  2.42E+3nMAssay Description:Displacement of [3H]PGE2 from human EP2R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  2.44E+3nMAssay Description:Displacement of [3H]PGE2 from human EP1R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4R expressed in chem1 cells after 2hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50193918(3-(2-((E)-3-(4-(benzyloxy)-3-methoxyphenyl)prop-1-...)
Affinity DataKi:  8.70E+3nMAssay Description:Binding affinity to EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed