BDBM50194087 1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fluoren-4-yl)phenoxy]ethyl}piperidine::CHEMBL210063

SMILES Oc1ccc2C3=C(C(=O)CCC3(Cc3ccccc3)Cc2c1)c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=GFKGHNYRKPBMSP-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194087   

TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  180nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataEC50:  14nMAssay Description:Activity at ERalpha L384M/M421G/G521R mutant in HeLa cells assessed as activation of SEAP reporter geneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  380nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed