BDBM50195944 CHEMBL219721::N-{2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl}-2-(2-oxo-3-phenyl-2,3-dihydro-1H-1,3-benzodiazol-1-yl)acetamide

SMILES O=C(Cn1c2ccccc2n(-c2ccccc2)c1=O)Nc1ccc2CC3(Cc2c1)NC(=O)NC3=O

InChI Key InChIKey=PERWLMFLRFZYEH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195944   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195944(CHEMBL219721 | N-{2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataKi:  87nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195944(CHEMBL219721 | N-{2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataIC50:  430nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed