BDBM50196033 2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide::2,3,4-trihydroxy-5-isopropyl-N-phenylbenzamide::CHEMBL214839

SMILES CC(C)c1cc(C(=O)Nc2ccccc2)c(O)c(O)c1O

InChI Key InChIKey=HMVKMSUSFWLQLX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196033   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196033(2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide | ...)
Affinity DataKi:  2.41E+4nMAssay Description:Displacement of FAM-Bid from human Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196033(2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide | ...)
Affinity DataKi:  3.19E+4nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196033(2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide | ...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of growth of human PC3 cell overexpressing Bcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196033(2,3,4-trihydroxy-5-isopropyl-N-phenyl-benzamide | ...)
Affinity DataIC50:  5.31E+4nMAssay Description:Binding affinity to human Bcl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed