BDBM50197105 (2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine::CHEMBL384123
SMILES N[C@@H]([C@H]1CC[C@H]1C(O)=O)C(O)=O
InChI Key InChIKey=SRAFHGOPGVYULO-LMVFSUKVSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50197105
Affinity DataKi: 6.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 5.20E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair