BDBM50197216 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2-dimethyl-1H-imidazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234774

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1cn(C)c(C)n1)C(=O)NO

InChI Key InChIKey=XAISFEMYYICOMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197216   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197216(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197216(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2...)
Affinity DataIC50:  147nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197216(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed