BDBM50197225 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dimethylisoxazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-({[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}METHYL)-1-[(3,5-DIMETHYLISOXAZOL-4-YL)SULFONYL]-N-HYDROXYPIPERIDINE-4-CARBOXAMIDE::CHEMBL234567

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1c(C)noc1C)C(=O)NO

InChI Key InChIKey=BIGQJQKSDHOEOM-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197225   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197225(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197225(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197225(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50:  664nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197225(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5...)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed