BDBM50197228 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5-dichlorothiophen-3-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234776

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1cc(Cl)sc1Cl)C(=O)NO

InChI Key InChIKey=PRHFUFABVIQNBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197228   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197228(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5...)
Affinity DataIC50: <1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197228(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5...)
Affinity DataIC50:  23nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197228(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5...)
Affinity DataIC50:  22nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed