BDBM50197237 1-(4-acetylpiperazin-1-ylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL231877

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCN(CC1)C(C)=O)C(=O)NO

InChI Key InChIKey=WUVJCBZUUQXYIT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197237   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197237(1-(4-acetylpiperazin-1-ylsulfonyl)-4-((4-(but-2-yn...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197237(1-(4-acetylpiperazin-1-ylsulfonyl)-4-((4-(but-2-yn...)
Affinity DataIC50:  104nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50197237(1-(4-acetylpiperazin-1-ylsulfonyl)-4-((4-(but-2-yn...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of TACE in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed