BDBM50198033 CHEMBL227484::[(R)-2-methyl-1-(4'-methyl-biphenyl-4-sulfonylamino)-propyl]-phosphonic acid

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)P(O)(O)=O

InChI Key InChIKey=CJTUBZULFXKTAT-QGZVFWFLSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50198033   

TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  98nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  98nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed