BDBM50198186 CHEMBL3944427::US10479798, Compound 19

SMILES COc1cc2c3C[C@H](N)[C@H](Oc3ccc2cc1S(C)(=O)=O)c1cc(F)c(F)cc1F

InChI Key InChIKey=SJNBVFRWTRWQOE-LAUBAEHRSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198186   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50198186(CHEMBL3944427 | US10479798, Compound 19)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of DPP4 (unknown origin) expressed in Sf9 cells using Gly-Pro-AMC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50198186(CHEMBL3944427 | US10479798, Compound 19)
Affinity DataIC50:  2nMAssay Description:Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50198186(CHEMBL3944427 | US10479798, Compound 19)
Affinity DataKd:  11nMAssay Description:Binding affinity to DPP4 (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed