BDBM50198492 CHEMBL217860::N-[(2S)-6-[(1,1-dioxo-1,4-thiomorpholin-4-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamid
SMILES CN([C@H]1CCc2cc(CN3CCS(=O)(=O)CC3)ccc2C1)C(=O)c1ccc(cc1)-c1ccc(F)cc1
InChI Key InChIKey=VRLORRTWDYVKNM-NDEPHWFRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50198492
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 755nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair