BDBM50199883 3,4‐Dichloroisocoumarin (2)::3,4-Dichloro-isochromen-1-one::3,4-dichloro-1H-isochromen-1-one::3,4-dichloroisocoumarin::CHEMBL24983::cid_1609
SMILES Clc1oc(=O)c2ccccc2c1Cl
InChI Key InChIKey=SUGXUUGGLDCZKB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50199883
TargetMitochondrial import inner membrane translocase subunit TIM10(Saccharomyces cerevisiae S288c)
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using KSp21 as substrate preincubated for 30 mins followed by substrate addition measured after 50 t...More data for this Ligand-Target Pair
TargetAN1-type domain-containing protein(Archaeoglobus fulgidus (AfROM))
Technische Universität München
Technische Universität München
Affinity DataIC50: 8.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (Euryarchaeotes))
Technische Universität München
Technische Universität München
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München
Technische Universität München
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München
Technische Universität München
Affinity DataIC50: 660nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (Firmicutes))
Technische Universität München
Technische Universität München
Affinity DataIC50: 4.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human leukocyte elastase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The compound was evaluated in vitro for the inhibition of human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:The compound was evaluated in vitro for the inhibition of rat leukocyte elastase(RLE)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:The compound was evaluated in vitro for the inhibition of pancreatitic porcine elastase(PPE)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant CatA using [14C]GS7340 substrateMore data for this Ligand-Target Pair
TargetRhomboid domain-containing protein(Aquifex aeolicus (Aquificales))
Technische Universität München
Technische Universität München
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair