BDBM50200589 2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl}-N-methyl-acetamide::CHEMBL391631

SMILES CNC(=O)CN1CN(c2ccccc2)C2(CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)C1=O

InChI Key InChIKey=KLWASKREVYRVHL-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50200589   

TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200589(2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpenty...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200589(2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpenty...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200589(2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpenty...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200589(2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpenty...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200589(2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpenty...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed