BDBM50201091 2-[(cis-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL375348

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CN1C[C@H](C)O[C@H](C)C1)C(F)(F)F

InChI Key InChIKey=YRAUBPBLFNFPPH-FSWDVZBNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201091   

TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201091(2-[(cis-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1-t...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of tetramethylrhodamine labeled RU486 binding to PR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201091(2-[(cis-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1-t...)
Affinity DataIC50:  450nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to MR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201091(2-[(cis-2,6-dimethylmorpholin-4-yl)methyl]-1,1,1-t...)
Affinity DataIC50:  38nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed