BDBM50201302 1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea::CHEMBL231511

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1

InChI Key InChIKey=MGVHMJGTUMNGFV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201302   

TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of Aurora B using 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  13nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed