BDBM50201588 (S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-3-methyl-N-(2,3,4-trimethoxyphenyl)butanamide::CHEMBL217059

SMILES COc1ccc(NC(=O)CC(C)(C)NCC(=O)N2CCC[C@H]2C#N)c(OC)c1OC

InChI Key InChIKey=ROILUYIDWRVROQ-AWEZNQCLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201588   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201588((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of FAP, sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201588((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50:  127nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201588((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201588((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed