BDBM50201597 (S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-N-(3,4-dimethoxyphenethyl)-3-methylbutanamide::CHEMBL217290

SMILES COc1ccc(CCNC(=O)CC(C)(C)NCC(=O)N2CCC[C@H]2C#N)cc1OC

InChI Key InChIKey=HDAROEOKOYDDTM-KRWDZBQOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201597   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201597((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of FAP, sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201597((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50:  232nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201597((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50201597((S)-3-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed