BDBM50201618 CHEBI:76138::Flunixin::SCH-14714::US11744839, Compound of formula 7

SMILES Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F

InChI Key InChIKey=NOOCSNJCXJYGPE-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 ITC

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201618   

TargetFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

US Patent

LigandBDBM50201618(CHEBI:76138 | Flunixin | SCH-14714 | US11744839, C...)Copy SMILESCopy InChI

Affinity DataKd:  270nMAssay Description:An enzyme activity assay for BLVRB was conducted. Since BLVRB catalyzes the NAD(P)H dependent readuction of FMN, changes in the NAD(P)H concentration...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

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In DepthDetails US PatentPDB3D Structure (crystal)
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TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Broad Institute

Curated by ChEMBL

LigandBDBM50201618(CHEBI:76138 | Flunixin | SCH-14714 | US11744839, C...)Copy SMILESCopy InChI

Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant DHODHMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
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