BDBM50202658 CHEMBL3893879::US10730889, Example 49::US11485745, Example 367
SMILES CC(C)(C)OC(=O)N1CCC2(CC2CNC(=O)N2Cc3ccncc3C2)CC1
InChI Key InChIKey=DLHHFYXNVIMXSY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50202658
Affinity DataIC50: 1.60nMAssay Description:Inhibition of NAMPT in human A2780 cells assessed as decrease in cell viability after 72 hrs by SRB assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Reversible inhibition of CYP2C9 in human liver microsomes using (S)-warfarin as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human full length C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta (DE3) cells using nicotinamide as substrate incuba...More data for this Ligand-Target Pair