BDBM50203281 CHEMBL3971895
SMILES Clc1cccc(c1)-c1c(C#N)c(=O)[nH]c2[nH]c(=O)[nH]c(=O)c12
InChI Key InChIKey=OLAIUOJBVWWLOO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50203281
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 98nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 52nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 296nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Indian Institute Of Technology
Curated by ChEMBL
Indian Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human TDO expressed in Escherichia cli Rosetta (DE3) pLysS using L-tryptophan as substrate preincubated for 1 h...More data for this Ligand-Target Pair