BDBM50203361 (3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-2-oxopyrazin-1(2H)-yl)butanamido)-4-oxo-7-phenylheptanoic acid::CHEMBL248508

SMILES CCC(C(=O)N[C@@H](CC(O)=O)C(=O)CCCc1ccccc1)n1cc(nc(Nc2nnn[nH]2)c1=O)C(C)(C)C

InChI Key InChIKey=PSEYKDQFSOGYNR-ZENAZSQFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50203361   

TargetCaspase-1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of human recombinant caspase 3 in NT2 by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50203361((3S)-3-(2-(3-(1H-tetrazol-5-ylamino)-5-tert-butyl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed