BDBM50204544 CHEMBL262766
SMILES Cc1nnsc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F
InChI Key InChIKey=XPRZIORDEVHURQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50204544
TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of TRPC5 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium release-activated calcium channel protein/Stromal interaction molecule 1(Rattus norvegicus)
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of ORAI/STIM1 in thapsigargin treated rat RBL2H3 cells assessed as reduction in store-operated calcium entry after 5 mins by fura-2-AM dye...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair