BDBM50205075 2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)(pyridin-2-ylmethyl)amino)acetic acid::CHEMBL245674

SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccn2)cc1)-c1ccccc1

InChI Key InChIKey=UGNCHYOBPJJLAH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50205075   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205075(2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataIC50:  90nMAssay Description:Displacement of fluorescein labeled ligand from PPARalpha receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205075(2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataEC50:  230nMAssay Description:Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205075(2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataEC50:  692nMAssay Description:Agonist activity at PPARalpha receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205075(2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataIC50:  2.90E+3nMAssay Description:Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed