BDBM50207486 1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea::1-{4-[3-amino-7-(2-methoxy-ethoxy)-1H-indazol-4-yl]-phenyl}-3-m-tolyl-urea::CHEMBL223528

SMILES COCCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12

InChI Key InChIKey=CPMMIVUAUOMULB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207486   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207486(1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207486(1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207486(1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207486(1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207486(1-(4-(3-amino-7-(2-methoxyethoxy)-1H-indazol-4-yl)...)
Affinity DataIC50:  34nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed