BDBM50207513 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea::CHEMBL223361::N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-[2-fluoro-5-(trifluoromethyl)

SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12

InChI Key InChIKey=JBAAMDZTSDRVLV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207513   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207513(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207513(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-...)
Affinity DataIC50:  151nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207513(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207513(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207513(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed