BDBM50208029 1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-imidazolidin-1-yl]-1-[2-(3-fluoro-phenyl)-2-oxo-ethyl]-pyrrolidinium::CHEMBL222449

SMILES C[N+]1(CC(=O)c2cccc(F)c2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=XONNUPKRLWJHEZ-HSGLFRJESA-O

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50208029   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208029(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Affinity DataKi:  3.01nMAssay Description:Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208029(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208029(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Affinity DataIC50:  7.80nMAssay Description:Activity at muscarinic M3 receptor in Albino Dunkin-Hartley guinea pig trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208029(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Activity at muscarinic M2 receptor in Albino Dunkin-Hartley guinea pig left atria assessed as inhibition of methacholine-induced bradycardiaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed