BDBM50208346 4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyrrolidin-3-yl)benzamide::CHEMBL389691

SMILES Cc1cc(COc2ccc(cc2)C(=O)N[C@H]2CN(C[C@@H]2c2n[nH]c(=O)[nH]2)C(=O)OC(C)(C)C)c2ccccc2n1

InChI Key InChIKey=SBINJYYFUVHVNU-UPVQGACJSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50208346   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208346(4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5...)
Affinity DataKi: >2.13E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208346(4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208346(4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5...)
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208346(4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5...)
Affinity DataKi: >5.03E+3nMAssay Description:Binding affinity to MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208346(4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5...)
Affinity DataIC50:  162nMAssay Description:Inhibition of pTACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed