BDBM50209393 2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-oxo-1,2-dihydropyridin-3-yl)-N-cyclopropyl-7-methyl-3H-benzo[d]imidazole-5-carboxamide::CHEMBL231510

SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O)C(=O)NC1CC1

InChI Key InChIKey=UHIYZXSEOHGEBS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209393   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209393(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209393(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209393(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209393(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed