BDBM50209763 CHEMBL3883792

SMILES OC1COc2cc(F)c(F)c(Nc3ccc(I)cc3F)c2NS(=O)(=O)C2(CC2)CC1O

InChI Key InChIKey=FENWEVRRFMFDBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209763   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50209763(CHEMBL3883792)
Affinity DataIC50:  400nMAssay Description:Inhibition of MEK1/2 in human HT-29 cells assessed as reduction in cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50209763(CHEMBL3883792)
Affinity DataIC50:  400nMAssay Description:Inhibition of MEK1/2 in human HT-29 cells assessed as reduction in cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed