BDBM50211045 CHEMBL232068::methyl 2-(naphthalen-2-yl)cyclohex-1-enecarboxylate

SMILES COC(=O)C1=C(CCCC1)c1ccc2ccccc2c1

InChI Key InChIKey=BLAXQDSTBRMZPC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211045   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211045(CHEMBL232068 | methyl 2-(naphthalen-2-yl)cyclohex-...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211045(CHEMBL232068 | methyl 2-(naphthalen-2-yl)cyclohex-...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211045(CHEMBL232068 | methyl 2-(naphthalen-2-yl)cyclohex-...)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211045(CHEMBL232068 | methyl 2-(naphthalen-2-yl)cyclohex-...)
Affinity DataKi:  8.10E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211045(CHEMBL232068 | methyl 2-(naphthalen-2-yl)cyclohex-...)
Affinity DataKi:  1.09E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed