BDBM50211374 CHEMBL2371967::c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7-Pip8-Trp9-Lys10)-NH2
SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O
InChI Key InChIKey=DFDCZNQATCGDRV-LNVKHAPMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50211374
Affinity DataEC50: 0.450nMAssay Description:Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair