BDBM50211848 2-(3-chlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic acid 4-fluorobenzylamide::CHEMBL389908

SMILES Fc1ccc(CNC(=O)c2cnc(Nc3cccc(Cl)c3)nc2C(F)(F)F)cc1

InChI Key InChIKey=XHWIJMYLOJKSST-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211848   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Saccharomyces cerevisiae cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211848(2-(3-chlorophenylamino)-4-trifluoromethylpyrimidin...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed