BDBM50212186 CHEMBL250120::N-((5R,14R)-5-amino-5-methyl-16-oxo-14-phenyl-3-oxa-15-aza-tricyclo[15.3.1.1*7,11*]docosa-1(21),7,9,11(22,17,19-hexaen-19-yl)-N-methyl-methanesulfonamide

SMILES CN(c1cc2COC[C@](C)(N)Cc3cccc(CC[C@@H](NC(=O)c(c2)c1)c1ccccc1)c3)S(C)(=O)=O

InChI Key InChIKey=QQXBXYNIOWQZOP-XRKRLSELSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212186   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212186(CHEMBL250120 | N-((5R,14R)-5-amino-5-methyl-16-oxo...)
Affinity DataIC50:  49nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed