BDBM50212699 2-(7-(4-(4-fluorobenzyloxy)benzylthio)-2,3-dihydro-1H-inden-4-yloxy)acetic acid::CHEMBL232399

SMILES OC(=O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3)cc2)c2CCCc12

InChI Key InChIKey=AXULCJXNLKWOCT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212699   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212699(2-(7-(4-(4-fluorobenzyloxy)benzylthio)-2,3-dihydro...)
Affinity DataEC50:  1.36E+4nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212699(2-(7-(4-(4-fluorobenzyloxy)benzylthio)-2,3-dihydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212699(2-(7-(4-(4-fluorobenzyloxy)benzylthio)-2,3-dihydro...)
Affinity DataIC50:  191nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed