BDBM50212700 2-(7-(4-(4-tert-butylbenzyloxy)benzylthio)-2,3-dihydro-1H-inden-4-yloxy)acetic acid::CHEMBL392949

SMILES CC(C)(C)c1ccc(COc2ccc(CSc3ccc(OCC(O)=O)c4CCCc34)cc2)cc1

InChI Key InChIKey=SNUCWTMFDGLTCI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212700   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212700(2-(7-(4-(4-tert-butylbenzyloxy)benzylthio)-2,3-dih...)
Affinity DataIC50:  1.54E+3nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212700(2-(7-(4-(4-tert-butylbenzyloxy)benzylthio)-2,3-dih...)
Affinity DataEC50:  267nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212700(2-(7-(4-(4-tert-butylbenzyloxy)benzylthio)-2,3-dih...)
Affinity DataIC50:  148nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed