BDBM50213092 (1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cyclohexane::CHEMBL387671

SMILES C(Cc1cccc2ccccc12)O[C@@H]1CCCC[C@H]1N1CCOCC1

InChI Key InChIKey=JQQLXARPNNPHPC-FGZHOGPDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213092   

TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213092((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed