BDBM50213094 (1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholinyl)cyclohexane::CHEMBL387935

SMILES Clc1ccc(CCO[C@@H]2CCCC[C@H]2N2CCOCC2)cc1Cl

InChI Key InChIKey=XYNMOULGJNGXPD-QZTJIDSGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213094   

TargetPotassium voltage-gated channel subfamily B member 1(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 2(Rattus norvegicus)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213094((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed