BDBM50213099 (R,R)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylamino-propane::CHEMBL228992::US10617654, Compound (R,R)-2::US9492405, (R,R)-2::US9492405, 32
SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
InChI Key InChIKey=WHAUNCTVVNUUIP-XIKOKIGWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50213099
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 474nM ΔG°: -8.01kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 2.20E+4nM ΔG°: -5.90kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 0.170nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR,
1321N1 or U87MG cells were seeded in a 96-well plate at approximately
5,000 c...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKd: 479nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair