BDBM50213530 CHEMBL228659::N-((1s,4s)-4-(4-(5-fluoro-2-isopropoxyphenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide

SMILES COc1ccc(cc1OC)S(=O)(=O)N[C@H]1CC[C@H](CC1)N1CCC(CC1)c1cc(F)ccc1OC(C)C

InChI Key InChIKey=AEJCTJSNUNXYQL-ZRZAMGCNSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213530   

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213530(CHEMBL228659 | N-((1s,4s)-4-(4-(5-fluoro-2-isoprop...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human cloned adrenergic alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213530(CHEMBL228659 | N-((1s,4s)-4-(4-(5-fluoro-2-isoprop...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to human cloned adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213530(CHEMBL228659 | N-((1s,4s)-4-(4-(5-fluoro-2-isoprop...)
Affinity DataKi:  178nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50213530(CHEMBL228659 | N-((1s,4s)-4-(4-(5-fluoro-2-isoprop...)
Affinity DataKi:  299nMAssay Description:Binding affinity to human cloned adrenergic alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed