BDBM50213535 5-chloro-2-fluoro-N-((1r,4r)-4-(4-(2-(2,2,2-trifluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)benzenesulfonamide::CHEMBL228494

SMILES Fc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@@H](CC1)N1CCC(CC1)c1ccccc1OCC(F)(F)F

InChI Key InChIKey=HNTIGZIKHBPAFD-MXVIHJGJSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213535   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213535(5-chloro-2-fluoro-N-((1r,4r)-4-(4-(2-(2,2,2-triflu...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to human cloned adrenergic alpha1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213535(5-chloro-2-fluoro-N-((1r,4r)-4-(4-(2-(2,2,2-triflu...)
Affinity DataKi:  37nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213535(5-chloro-2-fluoro-N-((1r,4r)-4-(4-(2-(2,2,2-triflu...)
Affinity DataKi:  44nMAssay Description:Binding affinity to human cloned adrenergic alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213535(5-chloro-2-fluoro-N-((1r,4r)-4-(4-(2-(2,2,2-triflu...)
Affinity DataKi:  787nMAssay Description:Binding affinity to human cloned adrenergic alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed