BDBM50214012 CHEMBL394368::N-(4-((1-(2-fluorobenzyl)-3-(cyclopropylmethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)methyl)phenyl)-3,5-dimethylisoxazole-4-sulfonamide

SMILES Cc1noc(C)c1S(=O)(=O)Nc1ccc(Cc2nc3n(CC4CC4)c(=O)n(Cc4ccccc4F)c(=O)c3[nH]2)cc1

InChI Key InChIKey=IVBLVHSUXQCZKG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214012   

TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214012(CHEMBL394368 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214012(CHEMBL394368 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed