BDBM50218545 Nitraquazone

SMILES CCn1c(=O)n(-c2cccc(c2)[N+]([O-])=O)c2ccccc2c1=O

InChI Key InChIKey=GNWCRBFQZDJFTI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50218545   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of phosphodiesterase 4 in rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of [3H]rolipram binding to rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed