BDBM50219453 4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl)-1-naphthonitrile::CHEMBL392500

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccc(C#N)c2ccccc12)C(F)(F)F

InChI Key InChIKey=UGJGTPGLSLQCPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219453   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219453(4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50:  430nMAssay Description:Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219453(4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50:  21nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219453(4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)
Affinity DataIC50:  325nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed