BDBM50219638 CHEMBL247822::N-(4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES Fc1ccc(cc1C(F)(F)F)-c1csc(NC(=O)c2ccc(Nc3ccncn3)cc2)n1

InChI Key InChIKey=LPXOUFHVYNPPSB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219638   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219638(CHEMBL247822 | N-(4-(4-fluoro-3-(trifluoromethyl)p...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219638(CHEMBL247822 | N-(4-(4-fluoro-3-(trifluoromethyl)p...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219638(CHEMBL247822 | N-(4-(4-fluoro-3-(trifluoromethyl)p...)
Affinity DataEC50:  104nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed