BDBM50219644 CHEMBL248390::N-(5-chloro-4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-4-(6-(dimethylamino)pyrimidin-4-ylamino)benzamide

SMILES CN(C)c1cc(Nc2ccc(cc2)C(=O)Nc2nc(c(Cl)s2)-c2ccc(F)c(c2)C(F)(F)F)ncn1

InChI Key InChIKey=AAIUODNJTNMLJB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219644   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219644(CHEMBL248390 | N-(5-chloro-4-(4-fluoro-3-(trifluor...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed