BDBM50219648 CHEMBL248388::N-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-5-methylthiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES Cc1sc(NC(=O)c2ccc(Nc3ccncn3)cc2)nc1-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=DVGGFAIKQGEVTG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219648   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219648(CHEMBL248388 | N-(4-(4-fluoro-3-(trifluoromethyl)p...)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed