BDBM50220232 (S)-benzyl 4-(5-((2-aminophenyl)carbamoyl)pyridin-2-yl)-2-methylpiperazine-1-carboxylate::(S)-benzyl 4-(5-(2-aminophenylcarbamoyl)pyridin-2-yl)-2-methylpiperazine-1-carboxylate::CHEMBL236902
SMILES C[C@H]1CN(CCN1C(=O)OCc1ccccc1)c1ccc(cn1)C(=O)Nc1ccccc1N
InChI Key InChIKey=UQKHQHYWAJFGDY-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50220232
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 942nMAssay Description:Inhibition of human HDAC3 expressed in mammalian cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant HDAC8More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.52E+3nMAssay Description:Activity against human MAPK3More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Activity against human serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 939nMAssay Description:Inhibition of recombinant HDAC3More data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant HDAC2More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC1 expressed in mammalian cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 308nMAssay Description:Inhibition of human HDAC2 expressed in mammalian cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.12E+3nMAssay Description:Activity against human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair